I gotta say, after listening to a lot of Sword and Scale, and then the latest Slate podcast (which is extra spoilery and includes outside information, including a very plausible alternate theory of the crime), I feel surprisingly confident that Adnan is innocent.
When the innocence project lawyer said that Adnan would have to be a perfect sociopath, I kind of blew that off at the time, but she really is right. Hearing many voices of actual sociopaths & psychopaths on Sword and Scale, then hearing Adnan, there seems to be no connection. To me it sounds like he has that basic emotional inner life that's missing in psychopaths. Unless he really is a master manipulator.