I used to play Fallout and Fallout 2 obsessively. They are still my favorite games ever.
Just started playing New Vegas. Who knows why I waited so long... Probably because I'm not a console person and I dislike having to bootcamp into Windows. (Yes I tried the wineskin version and it's garbage for several reasons.)
I'm still getting used to the FPS element. I was deeply attached to the overhead view and turn-based combat of the originals. So I'm using a VATS-centric build, which is actually a lot of fun. Until I level up a bit, the best strategy seems to be to rush people and headshot them with VATS.
That didn't work as well when I encountered a pack of 6-7+ baddies wielding meat cleavers and grenade launchers. But I adjusted.
I am enjoying it quite a bit. Traveling to new places can be tiresome, but I'm trying to have patience with that. The sense of discovery has more or less been as potent as ever. As long as there is enough to encounter along the highway and such, that shouldn't be a problem.
My only real complaint is that I can't steal things without consequences. That was one of my favorite things about the originals, going through everyone's stuff and pickpocketing my friends. How meaningful is the loss of Karma in New Vegas?